Successful use of bivalirudin for superior vena cava recanalization and stent placement in a child with heparin-induced thrombocytopenia

JP Breinholt, BS Moffett, KM Texter, FF Ing - Pediatric cardiology, 2008 - Springer
JP Breinholt, BS Moffett, KM Texter, FF Ing
Pediatric cardiology, 2008Springer
Heparin-induced thrombocytopenia (HIT) is a potentially life-threatening, adverse effect of
heparin therapy. Patients with this complication require an alternative approach to
anticoagulation. Bivalirudin is a direct thrombin inhibitor with an efficacy comparable to that
of heparin, a short half-life, and reduced bleeding complications in adults. We present the
case of a 2-year-old boy with HIT Type II who underwent recanalization of an occluded
superior vena cava and stent placement, utilizing bivalirudin as anticoagulant.
Abstract
Heparin-induced thrombocytopenia (HIT) is a potentially life-threatening, adverse effect of heparin therapy. Patients with this complication require an alternative approach to anticoagulation. Bivalirudin is a direct thrombin inhibitor with an efficacy comparable to that of heparin, a short half-life, and reduced bleeding complications in adults. We present the case of a 2-year-old boy with HIT Type II who underwent recanalization of an occluded superior vena cava and stent placement, utilizing bivalirudin as anticoagulant.
Springer
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